The bad blood between Donald Trump and Rosie O'Donnell has boiled over again after the Republican presidential candidate at Monday's presidential debate tried to justify calling the raucous comedienne "a pig" and criticizing her weight.
In a profane tweet on Tuesday, O'Donnell referred to Trump as "an orange anus" — a crude reference to his unusual, flame-tinted hair color.
O'Donnell delivered the slap after Trump's response to Hillary Clinton, who in the closing minutes of the debate described him as "a man who has called women pigs, slobs and dogs."
Trump — who's made fun of O'Donnell's weight and called her "a pig," "a slob" and "a total degenerate" — shot back: "Rosie O'Donnell, I said very tough things to her and I think everyone would agree that she deserves it and nobody feels sorry for her."
Aside from comparing Trump to an oddly-shaded derriere, O'Donnell also tweeted:
Also weighing in on the latest Trump-O'Donnell fisticuffs was Madonna.
The Material Girl — who is one of O'Donnell's close friends after starring with her in the 1992 baseball comedy "A League of Their Own" — tweeted:
According to TheWrap.com, O'Donnell claims the source of her bad blood with Trump was an impression she did of him on ABC's "The View" in 2006.