The National Transportation Safety Board investigators are headed to the scene of an Amtrak accident in Philadelphia that killed at least five people and injured dozens of others.
Northeast Regional Train 188 was headed to New York from Washington when it derailed in the city's Port Richmond section shortly after 9 p.m. Tuesday.
More than 140 people went to hospitals to be evaluated or treated, and six were critically injured.
The derailment has closed a major section of the nation's busiest rail corridor. It is having an impact on commuter rails.
Mayor Michael Nutter called the scene "an absolute disastrous mess."
The mayor says all seven train cars, including the engine, were in "various stages of disarray."
He said there were cars that were "completely overturned, on their side, ripped apart."
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