Medical marijuana may offer relief for some migraine sufferers, a new study suggests.

Patients with migraine headaches experienced a significant drop in their frequency when treated with weed, according to researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of Colorado Anschutz Medical Campus, Medical Xpress reports.

The study, published in the journal Pharmacotherapy, tracked 121 patients diagnosed with migraines and treated with medical marijuana between 2010 and 2014. It found the frequency of migraines dropped from 10.4 to 4.6 headaches per month. In addition, 103 of the patients reported a decrease in monthly migraines.

"There was a substantial improvement for patients in their ability to function and feel better," said researcher Laura Borgelt. "Like any drug, marijuana has potential benefits and potential risks. It's important for people to be aware that using medical marijuana can also have adverse effects."

Exactly how cannabis relieves migraines is still not fully understood. Borgelt suggested it may have anti-inflammatory and pain-relieving properties and affect critical neurotransmitters like serotonin and dopamine.

"We believe serotonin plays a role in migraine headaches, but we are still working to discover the exact role of cannabinoids in this condition," Borgelt said.